Fas Ligand, soluble human, recombinant, expressed in HEK 293 cells, lyophilized powder

Code: S8689-5UG D2-231

Application

ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes....


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£713.00 5UG
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Application

ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFasL™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

Biochem/physiol Actions

Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation.

Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).

Legal Information

SuperFas Ligand is a trademark of Alexis Biochemicals Corp.

assay≥95% (SDS-GE)
biological sourcehuman
formlyophilized powder
Gene Informationhuman ... FASLG(356)
mol wt32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)
Quality Level200
recombinantexpressed in HEK 293 cells
storage temp.−20°C
technique(s)ligand binding assay: suitable
UniProt accession no.P48023
This product has met the following criteria: