Human growth differentiation factor 15 (GDF-15) protein is a member of the TGFβ family and subject of intense interest as a marker of cellular stress and for its role in metabolism, cancer and pregnancy. Human GDF-15 also is functional in mouse studies.
Qkine GDF-15 is a 25 kDa disulphide-linked dimer composed of the mature domain of human GDF-15 protein. Our recombinant GDF-15 protein is exceptionally high purity, animal origin-free and extensively validated to ensure no trace contamination of related TGF-β family proteins from the mammalian culture systems.
- High purity human GDF-15 protein (Uniprot: Q99988)
- >98%, by SDS-PAGE quantitative densitometry
- 25 kDa (dimer). Mature active protein is a disulphide-linked dimer
- Expressed in E. coli
- Animal origin-free (AOF)
- Carrier protein-free
- Manufactured in our Cambridge, UK laboratories
- Lyophilised from acetonitrile, TFA
- Resuspend in 10mM HCl at >100µg/mL (provided with protein and free of charge), prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C