Nimodipine, pharmaceutical secondary standard; traceable to USP, PhEur and BP

Code: PHR1293-1G D2-231

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Application...


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£156.34 1G
£187.61 inc. VAT

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nimodipine can be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations and combined dosage forms by various electrochemical and spectrophotometric techniques.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA0583 in the slot below. This is an example certificate only and may not be the lot that you receive.

General description

Nimodipine is a well-known calcium antagonist and is a moderate cerebral vasodilator, in addition to being an inhibitor of cerebrovascular reactivity. It is suggested to be cytoprotective by causing a decrease in the influx of calcium into the nerve cells. It is accepted for use in the management of delayed ischaemic dysfunction and is commonlly used in the studies of brain function impairment and dementia in old age.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

agencytraceable to Ph. Eur. N0850000, traceable to BP 651, traceable to USP 1463858
application(s)pharmaceutical (small molecule)
CofAcurrent certificate can be downloaded
formatneat
Gene Informationhuman ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), NR3C2(4306)
gradepharmaceutical secondary standard, certified reference material
InChI keyUIAGMCDKSXEBJQ-UHFFFAOYSA-N
InChI1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
Quality Level300
SMILES stringCOCCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OC(C)C
storage temp.2-8°C
technique(s)gas chromatography (GC): suitable, HPLC: suitable
Cas Number66085-59-4
This product has met the following criteria: