beta-Estradiol-Water Soluble, BioReagent, suitable for cell culture

Code: E4389-100MG D2-231

Application

β-estradiol has been used:to culture differentiated adipocytesfor estradiol treatment in ratsfor oocyte maturation in vitroβ-Estradiol is used to study c...


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£260.00 100MG
£312.00 inc. VAT
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Application

β-estradiol has been used:to culture differentiated adipocytesfor estradiol treatment in ratsfor oocyte maturation in vitroβ-Estradiol is used to study cell differentiation and transformations (tumorigenicity). This product is not recommended for use in binding assays.

General description

β-estradiol is a natural humanestrogen. It is vital for the growth of breast and reproductive epithelia, maturation of long bones and development of secondary sexual characteristics. Estradiol is produced by immature germ cells, spermatozoa, Leydig cells and Sertoli cells. β-estradiol acts as a menopausal hormones. It is involved in replacement therapy for female hypogonadism or primary ovarian failure. Reduced levels of β-estradiol are linked to heart disease and osteoporosis. Estradiol plays a critical role in proliferation, modulation of ion transport and control of apoptosis in Sertoli cells. It maintains sperm concentration, motility and morphology.

Other Notes

Contains 40-55mg estradiol per gram of solid; balance 2-hydroxypropyl-β-cyclodextrin.

Packaging

Package size based on estradiol

100 mg in poly bottle

biological sourcesynthetic (organic)
formpowder
InChI keyXMURHKLFGRLVRW-JKDYGSMVSA-N
InChI1S/C46H78O35.C18H24O2/c1-12-20(55)40-68-13(5-48)32(12)75-41-26(61)25(60)37(18(10-53)69-41)81-46-39(67-4-2-3-47)31(66)38(19(11-54)74-46)80-45-30(65)24(59)36(17(9-52)73-45)79-44-29(64)23(58)35(16(8-51)72-44)78-43-28(63)22(57)34(15(7-50)71-43)77-42-27(62)21(56)33(76-40)14(6-49)70-42;1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h12-66H,2-11H2,1H3;3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31+,32+,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-;14-,15-,16+,17+,18+/m11/s1
product lineBioReagent
Quality Level200
shipped inambient
SMILES stringC[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O.C[C@@H]5[C@@H](O)[C@@H]6O[C@H](CO)[C@H]5O[C@H]7O[C@H](CO)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O[C@H]9O[C@H](CO)[C@@H](O[C@H]O[C@H](CO)[C@@H](O[C@H]O[C@H](CO)[C@@H](O[C@H]O[C@H](CO)[C@@H](O6)[C@H](O)[C@H]O)[C@H](O)[C@H]O)[C@H](O)[C@H]O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8OCCCO)[C@H](O)[C@H]7O
solubilityH2O: 25 mg/mL, clear to slightly hazy
sterilitynon-sterile
storage temp.room temp
technique(s)cell culture | mammalian: suitable
Pack100MG
This product has met the following criteria: