General description

SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.
Recombinant human SDF-1β is an 8.5 kDa protein containing 72 amino acid residues.

Quality

Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentration range of 20.0- 80.0 ng/ml.