Ro 15-4513, solid

Code: R109-100MG D2-231

Application

Ro 15-4513 has been used as a benzodiazepine (Bz) inverse agonist in rats and to test its binding with diazepam-sensitive (DS) receptors in in vitro radi...


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£1,410.00 100MG
£1,692.00 inc. VAT
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Application

Ro 15-4513 has been used as a benzodiazepine (Bz) inverse agonist in rats and to test its binding with diazepam-sensitive (DS) receptors in in vitro radioligand binding studies.

Biochem/physiol Actions

Ro 15-4513 is benzodiazepine receptor partial inverse agonist. It elicits anxiogenic property and is an ethanol antagonist. It elicits a high affinity towards diazepam sensitive and insensitive sites in the cerebellar region. Ro 15-4513 possesses an imidazo ring and is an imidazobenzodiazepine.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

25, 100 mg in poly bottle

colortan
formsolid
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559)rat ... Gabrg1(140674)
InChI keyCFSOJZTUTOQNIA-UHFFFAOYSA-N
InChI1S/C15H14N6O3/c1-3-24-15(23)13-12-7-20(2)14(22)10-6-9(18-19-16)4-5-11(10)21(12)8-17-13/h4-6,8H,3,7H2,1-2H3
originatorRoche
Quality Level100
SMILES stringCCOC(=O)c1ncn-2c1CN(C)C(=O)c3cc(ccc-23)N=[N+]=[N-]
solubility45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL, methanol: soluble, H2O: insoluble
Code
Description
Unit Size
List Price
Qty
R109-25MG
Ro 15-4513, solid

Unit:25MG
List Price: £417.00
Source:List Price
ADD
Cas Number91917-65-6
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